AN OPEN-SOURCE SOFTWARE ANALYSIS PACKAGE FOR MICROSPHERES WITH RATIOMETRIC BARCODE LANTHANIDE ENCODING (MRBLES).

An open-source software analysis package for Microspheres with Ratiometric Barcode Lanthanide Encoding (MRBLEs).

Multiplexed bioassays, in which multiple analytes of interest are probed in parallel within a single small volume, have greatly accelerated the pace of biological discovery.Bead-based multiplexed bioassays have many technical advantages, including near solution-phase kinetics, small sample volume requirements, many within-assay replicates to reduce

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Consequences of group III/IV afferent feedback and respiratory muscle work on exercise tolerance in heart failure with reduced ejection fraction

Abstract Exercise intolerance and exertional dyspnoea are the cardinal symptoms of heart failure with reduced ejection fraction (HFrEF).In HFrEF, abnormal autonomic and cardiopulmonary responses arising from locomotor muscle group III/IV afferent feedback is one of the primary mechanisms contributing to exercise intolerance.HFrEF patients also have

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Approaches to the Management of Hypertension in Resource-Limited Settings: Strategies to Overcome the Hypertension Crisis in the Post-COVID Era

Jamario Skeete,1 Kenneth Connell,2 Pedro Ordunez,3 Donald J DiPette4 1Division of Cardiology, Department of Internal Medicine, Rush University Medical Center, Chicago, IL, USA; 2Faculty of Medical Sciences, University of the West Indies, Cave Hill Campus, St.Michael, Barbados; 3Department of Non-Communicable Diseases and Mental Health, Pan-American

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